It starts with a strange Indian running from Doc Savage’s office building. Then rich and powerful men begin to disappear. Doc and his men follow the trail to the Amazon jungles where they must contend with man eating fish, deadly jungle cats, an unknown tribe of Indians, and, worst of all, New York gangsters willing to do anything to obtain the secret of Jaguar Valley.
A bank robber who laughs himself to death leads the Man of Bronze and his friends on the trail West where they must face laughing lunatics and flaming corpses. But can even Doc Savage survive where he comes face to face with the Master of Fear?